Exclusive expression of C. elegans osm-3 kinesin gene in chemosensory neurons open to the external environment.

@article{Tabish1995ExclusiveEO,
  title={Exclusive expression of C. elegans osm-3 kinesin gene in chemosensory neurons open to the external environment.},
  author={M Tabish and Zahid Kamal Siddiqui and Ken Nishikawa and Shahid S. Siddiqui},
  journal={Journal of molecular biology},
  year={1995},
  volume={247 3},
  pages={377-89}
}
In Caenorhabditis elegans three genetic loci osm-3, unc-104 and unc-116 have been identified, which encode anterograde motor kinesin. Here we show that osm-3 encodes a 672 amino acid long kinesin-like protein (KLP) that contains all three functional domains similar to the kinesin heavy chain, including a globular motor region, an alpha-helical coiled-coil rod, and a globular tail region. OSM-3 shows homology in both the motor and rod domains with kinesins from divergent species such as mouse… CONTINUE READING
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