Exclusion of elderly subjects from clinical trials for Parkinson disease.

  title={Exclusion of elderly subjects from clinical trials for Parkinson disease.},
  author={Susan L. Mitchell and Erin A Sullivan and Lewis A. Lipsitz},
  journal={Archives of neurology},
  volume={54 11},
OBJECTIVES To determine whether subjects older than 75 years are included in the randomized controlled trials of antiparkinsonian medications conducted during the last 30 years and to identify study characteristics that are associated with the exclusion of patients of advanced age. METHODS A systematic search was conducted on MEDLINE from January 1966 until September 1996 of all randomized controlled trials of drugs used to treat the motor symptoms of Parkinson disease. Articles were… CONTINUE READING
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