Exclusion of CD45 from the T-cell receptor signaling area in antigen-stimulated T lymphocytes

Abstract

T lymphocytes are activated by the engagement of their antigen receptors (TCRs) with complexes of peptide and major histocompatibility complex (MHC) molecules displayed on the cell surface of antigen-presenting cells (APCs) [1]. An unresolved question of antigen recognition by T cells is how TCR triggering actually occurs at the cell-cell contact area. We… (More)
DOI: 10.1016/S0960-9822(00)00362-6

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@article{Leupin2000ExclusionOC, title={Exclusion of CD45 from the T-cell receptor signaling area in antigen-stimulated T lymphocytes}, author={Olivier Leupin and Rossana Zaru and Thierry Laroche and Sabina Mueller and S. Valitutti}, journal={Current Biology}, year={2000}, volume={10}, pages={277-280} }