Excitotoxic spinal cord injury: behavioral and morphological characteristics of a central pain model

@article{Yezierski1998ExcitotoxicSC,
  title={Excitotoxic spinal cord injury: behavioral and morphological characteristics of a central pain model},
  author={R. Yezierski and S. Liu and G. Ruenes and K. Kajander and K. Brewer},
  journal={Pain},
  year={1998},
  volume={75},
  pages={141-155}
}
&NA; Intraspinal injections of the AMPA‐metabotropic receptor agonist quisqualic acid (QUIS) were made in an effort to simulate injury induced elevations of excitatory amino acids (EAAs), a well documented neurochemical change following spinal cord injury (SCI). The progressive pathological sequela associated with QUIS injections closely resembles the cascade of events described following ischemic and traumatic SCI and the pathogenesis of cavities in the clinical condition of post‐traumatic… Expand
250 Citations
Chronic, Selective Forebrain Responses to Excitotoxic Dorsal Horn Injury
Mechanisms of chronic central neuropathic pain after spinal cord injury
Agmatine reverses pain induced by inflammation, neuropathy, and spinal cord injury.
Gliopathy ensures persistent inflammation and chronic pain after spinal cord injury
...
1
2
3
4
5
...

References

SHOWING 1-10 OF 96 REFERENCES
A potential role for excitotoxins in the pathophysiology of spinal cord injury
Chronic central pain after spinal cord injury.
Neuronal degeneration and spinal cavitation following intraspinal injections of quisqualic acid in the rat.
Pain following spinal cord injury: the clinical problem and experimental studies
Deafferentation in animals as a model for the study of pain: an alternative hypothesis
...
1
2
3
4
5
...