Excitotoxic lesions of the pre- and parasubiculum disrupt the place fields of hippocampal pyramidal cells.

@article{Liu2004ExcitotoxicLO,
  title={Excitotoxic lesions of the pre- and parasubiculum disrupt the place fields of hippocampal pyramidal cells.},
  author={Ping Liu and Leonard E. Jarrard and David K Bilkey},
  journal={Hippocampus},
  year={2004},
  volume={14 1},
  pages={107-16}
}
To determine what influence the pre- and parasubiculum regions of the hippocampal formation have on neural representations within the dorsal hippocampus, single-unit recordings were made as rats with bilateral ibotenic acid lesions centered on the former regions (n = 4) or control surgeries (n = 3) foraged freely. Spatial firing specificity was measured using an information content procedure. Cells from lesioned animals (n = 57) provided significantly less spatial information than cells from… CONTINUE READING