Excitotoxic lesions of the pedunculopontine tegmental nucleus in rats impair performance on a test of sustained attention

@article{Kozak2004ExcitotoxicLO,
  title={Excitotoxic lesions of the pedunculopontine tegmental nucleus in rats impair performance on a test of sustained attention},
  author={Rouba Kozak and Eric M. Bowman and Mary P. Latimer and Claire L. Rostron and Philip Winn},
  journal={Experimental Brain Research},
  year={2004},
  volume={162},
  pages={257-264}
}
Recent research has suggested that the pontomesencephalic tegmentum might be an important part of a network underlying sustained attention. The largest structure of the pontomesencephalic tegmentum is the pedunculopontine tegmental nucleus, which has ascending connections to thalamus and with corticostriatal systems. In this experiment we examined the performance of rats following bilateral excitotoxic lesions of the pedunculopontine tegmental nucleus on a test of sustained attention previously… CONTINUE READING

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