Excitotoxic lesions of the core and shell subregions of the nucleus accumbens differentially disrupt body weight regulation and motor activity in rat.

@article{MaldonadoIrizarry1995ExcitotoxicLO,
  title={Excitotoxic lesions of the core and shell subregions of the nucleus accumbens differentially disrupt body weight regulation and motor activity in rat.},
  author={C. S. Maldonado-Irizarry and Ann E. Kelley},
  journal={Brain research bulletin},
  year={1995},
  volume={38 6},
  pages={551-9}
}
The behavioral effects of bilateral N-methyl-D-aspartate (NMDA) lesions of the core and medial shell subregions of the nucleus accumbens were evaluated in rats. Body weight was monitored for 2 weeks following surgery. Locomotor activity and open field behavior were recorded 1 week after surgery. The core-lesion group had difficulty recovering from the lesion and had significantly lower weights throughout the experiment. The shell-lesion group had normal recovery and weighed significantly more… CONTINUE READING

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