Excitatory orexinergic innervation of rat nucleus incertus – Implications for ascending arousal, motivation and feeding control

@article{Blasiak2015ExcitatoryOI,
  title={Excitatory orexinergic innervation of rat nucleus incertus – Implications for ascending arousal, motivation and feeding control},
  author={Anna Blasiak and Marcin Siwiec and Agnieszka Grabowiecka and Tomasz Blasiak and Andrew L Gundlach},
  journal={Neuropharmacology},
  year={2015},
  volume={99},
  pages={432-447}
}
Orexin/hypocretin peptides play a central role in the integrated control of feeding/reward and behavioural activation, principally via interactions with other neural systems. A brainstem area involved in behavioural activation is the nucleus incertus (NI), located in the posterior ventromedial central grey. Several studies have implicated NI in control of arousal/stress and reward/feeding responses. Orexin receptor mRNA expression identifies NI as a putative target of orexin modulation… CONTINUE READING
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