Excitatory amino acids depress synaptic currents in neonate rat sympathetic preganglionic neurons.

@article{Wu1993ExcitatoryAA,
  title={Excitatory amino acids depress synaptic currents in neonate rat sympathetic preganglionic neurons.},
  author={Sh. Ying Wu and Nae J. Dun},
  journal={Journal of neurophysiology},
  year={1993},
  volume={69 6},
  pages={2030-8}
}
1. Whole-cell patch-clamp recordings were made from sympathetic preganglionic neurons (SPNs) in transverse thoracolumbar spinal cord slices of 10- to 16-day-old rats, and the effects of L-glutamate (L-Glu) and analogues on excitatory (EPSCs) and inhibitory (IPSCs) postsynaptic currents evoked by stimulation of lateral funiculus were studied. 2. L-Glu (10-300 microM), quisqualate (QA, 0.1-3 microM), kainate (KA, 0.3-10 microM), ibotenate (10-25 microM), and L-2-amino-4-phosphonobutyrate (L-AP4… CONTINUE READING