Excitatory amino acids are released from rat primary afferent neurons in vitro

@article{Jeftinija1991ExcitatoryAA,
  title={Excitatory amino acids are released from rat primary afferent neurons in vitro},
  author={Srdija Jeftinija and Ksenija Jeftinija and Fang Liu and Stephen R. Skilling and David H. Smullin and Alice A. Larson},
  journal={Neuroscience Letters},
  year={1991},
  volume={125},
  pages={191-194}
}

Excitatory Amino Acid Release in Dorsal Root Ganglion Cultures

The present study used high K+ and chemical irritants capsaicin17,19 and bradykinin6,8,16 to evoke EAA release from organotypic DRG cultures which offer several advantages over in vivo and in vitro slice preparations.

Evidence for Glutamate as a Neuroglial Transmitter within Sensory Ganglia

Data provides additional evidence that glutamate can be released within the sensory ganglion, and that the somata of primary sensory neurons as well as SGCs express functional glutamate receptors at their surface, suggesting that glutamatergic transmission within the ganglions could impact nociceptive threshold.

Title Evidence for glutamate as a neuroglial transmitter withinsensory ganglia

Findings suggest that glutamatergic transmission within the ganglion could impact nociceptive threshold, and that the somata of primary sensory neurons as well as SGCs express functional glutamate receptors at their surface.
...

References

SHOWING 1-10 OF 17 REFERENCES

Coexistence of glutamate and substance P in dorsal root ganglion neurons of the rat and monkey

Neurons containing more than one antigen could be identified on adjacent sections tested with the three different antisera and the Glu antiserum, characterized by immunoadsorption and immunoblot tests, is highly selective for Glu out of a number of other amino acids including aspartate.

Extracellular Amino Acid Concentrations in the Dorsal Spinal Cord of Freely Moving Rats Following Veratridine and Nociceptive Stimulation

The hypothesis that Glu and Asp are dorsal horn neurotransmitters involved in nociception is supported.

Physiology and morphology of multireceptive neurons with C-afferent fiber inputs in the deep dorsal horn of the rat lumbar spinal cord.

The physiological properties of 12 multireceptive cells with A- and C-fiber inputs, whose cell body location was established by horseradish peroxidase ionophoresis and the morphology of six neurons in this group whose cell bodies lay within lamina V are described are described.

Supraspinal morphine and descending inhibitions acting on the dorsal horn of the rat.

The effects of microinjections of morphine on both the unconditioned C‐fibre‐evoked response and inhibitory processes triggered from the tail were investigated in an attempt to answer two questions: (a) does morphine increase tonic descending inhibitories processes and (b) what are the effects of Morphine on descending inhibition processes triggered by noxious stimuli.