Excitatory amino acid transporter 2 downregulation correlates with thalamic neuronal death following kainic acid-induced status epilepticus in rat.

@article{Sakurai2015ExcitatoryAA,
  title={Excitatory amino acid transporter 2 downregulation correlates with thalamic neuronal death following kainic acid-induced status epilepticus in rat.},
  author={Masashi Sakurai and Haruna Kurokawa and Akinori Shimada and Kazuhiro Nakamura and Hajime Miyata and Takehito Morita},
  journal={Neuropathology : official journal of the Japanese Society of Neuropathology},
  year={2015},
  volume={35 1},
  pages={1-9}
}
Recurrent seizures without interictal resumption (status epilepticus) have been reported to induce neuronal death in the midline thalamic region that has functional roles in memory and decision-making; however, the pathogenesis underlying status epilepticus-induced thalamic neuronal death is yet to be determined. We performed histological and immunohistochemical studies as well as cerebral blood flow measurement using 4.7 tesla magnetic resonance imaging spectrometer on midline thalamic region… CONTINUE READING