Excitatory amino acid receptors, neural membrane phospholipid metabolism and neurological disorders.

@article{Farooqui1991ExcitatoryAA,
  title={Excitatory amino acid receptors, neural membrane phospholipid metabolism and neurological disorders.},
  author={Akhlaq A. Farooqui and Lloyd A. Horrocks},
  journal={Brain research. Brain research reviews},
  year={1991},
  volume={16 2},
  pages={171-91}
}
Excitatory amino acids and their receptors play an important role in membrane phospholipid metabolism. Persistent stimulation of excitatory amino acid receptors by glutamate may be involved in neurodegenerative diseases and brain and spinal cord trauma. The molecular mechanism of neurodegeneration induced by excitatory amino acids is, however, not known. Excitotoxin induced calcium entry causes the stimulation of phospholipases and lipases. These enzymes act on neural membrane phospholipids and… CONTINUE READING