Excitatory amino acid antagonists and the anticonvulsive activity of conventional antiepileptic drugs.

@article{Kleinrok1995ExcitatoryAA,
  title={Excitatory amino acid antagonists and the anticonvulsive activity of conventional antiepileptic drugs.},
  author={Zdzisław Kleinrok and Waldemar Andrzej Turski and Stanisław Jerzy Czuczwar},
  journal={Polish journal of pharmacology},
  year={1995},
  volume={47 3},
  pages={247-52}
}
There is a great body of evidence, that excitatory amino acid antagonists, apart from their anticonvulsive properties per se, potentiate the protective activity of conventional antiepileptics against maximal electroshock-induced seizures in mice. It is worth stressing, that combinations of valproate with either CGP 37849 (a competitive NMDA antagonist) or… CONTINUE READING