Excitation of the squid giant axon by general anaesthetics.

@article{Haydon1988ExcitationOT,
  title={Excitation of the squid giant axon by general anaesthetics.},
  author={Daniel Haydon and Amos J. Simon},
  journal={The Journal of physiology},
  year={1988},
  volume={402},
  pages={375-89}
}
1. The effects of 'clinical' concentrations of some general anaesthetics on the minimum stimulus required to produce an action potential in the squid giant axon have been examined as a function of time from exposure to the anaesthetic. The resting potential in these experiments was also monitored. 2. The minimum stimulus varied with time in different ways for different anaesthetics. For chloroform, diethyl ether, n-pentanol, halothane and cyclopropane the stimulus initially declined, reached a… CONTINUE READING
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