Excision of cytosine-thymine adduct from the DNA of ultraviolet-irradiated Micrococcus radiodurans.

@article{Varghese1970ExcisionOC,
  title={Excision of cytosine-thymine adduct from the DNA of ultraviolet-irradiated Micrococcus radiodurans.},
  author={A. J. Varghese and Rufus S. Day},
  journal={Photochemistry and photobiology},
  year={1970},
  volume={11 6},
  pages={
          511-7
        }
}
— 6-4‘-[pyrimidin-2’-one]-thymine (PO-T), a deamination product of a cytosine–thymine adduct accounted for about 17 per cent of the total detectable thymine-derived photoproducts in u.v.-irradiated Micrococcus radiodurans. On incubation of the irradiated cells, oligonucleotides containing the photoproducts were released into the medium. After various periods of incubation the different photoproducts were isolated both from the cells and from the medium. Analysis of these different photoproducts… CONTINUE READING

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