Excipients in parenteral formulations: selection considerations and effective utilization with small molecules and biologics

@article{Rayaprolu2018ExcipientsIP,
  title={Excipients in parenteral formulations: selection considerations and effective utilization with small molecules and biologics},
  author={Bindhu Madhavi Rayaprolu and Jonathan J Strawser and Gopal Anyarambhatla},
  journal={Drug Development and Industrial Pharmacy},
  year={2018},
  volume={44},
  pages={1565 - 1571}
}
Abstract Excipients form a major component of pharmaceutical formulations and are classified as any ingredient other than the active ingredient which is included within the product formulation to improve drug product performance. Functional uses of excipients include improving solubility and stability, safety and efficacy, as bulking agents in lyophilized formulations, tonicity agents, and aiding in controlled or prolonged drug delivery. Parenteral formulations are sterile, pyrogen-free; free… Expand
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