Excessive eccentric exercise leads to transitory hypothalamic inflammation, which may contribute to the low body weight gain and food intake in overtrained mice

@article{Pereira2015ExcessiveEE,
  title={Excessive eccentric exercise leads to transitory hypothalamic inflammation, which may contribute to the low body weight gain and food intake in overtrained mice},
  author={Bruno Cesar Pereira and Andr{\'e}a Santos Leite da Rocha and Jos{\'e} Rodrigo Pauli and Eduardo Rochete Ropelle and A S R da Silva},
  journal={Neuroscience},
  year={2015},
  volume={311},
  pages={231-242}
}
Low body weight gain and food intake are related to exhaustive training and overtraining; however, the molecular mechanisms responsible for these alterations remain unknown. The main aim of this study was to evaluate the effects of running overtraining (OT) protocols performed downhill, uphill and without inclination on the inflammatory pathway in the mouse hypothalamus. The rodents were randomized into the control (C), overtrained by downhill running (OTR/down), overtrained by uphill running… CONTINUE READING
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