Excess weight gain during the early postnatal period is associated with permanent reprogramming of brown adipose tissue adaptive thermogenesis.

@article{Xiao2007ExcessWG,
  title={Excess weight gain during the early postnatal period is associated with permanent reprogramming of brown adipose tissue adaptive thermogenesis.},
  author={Xiao Qiu Xiao and Sarah M Williams and Bernadette E Grayson and Maria M. Glavas and Michael Alexander Cowley and M Susan Smith and Kevin L. Grove},
  journal={Endocrinology},
  year={2007},
  volume={148 9},
  pages={4150-9}
}
Excess weight gain during the early postnatal period increases the risk of persistent obesity into adulthood and impacts on the subsequent risk for metabolic and cardiovascular diseases. The current study investigated the long-term effect of early excess weight gain, through reduced nursing litter size, on body weight regulation and its relation to brown adipose tissue (BAT) thermogenesis. Animals raised in a small litter (SL, three pups per litter) were compared with those raised in a normal… CONTINUE READING

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