Excess purine degradation in exercising muscles of patients with glycogen storage disease types V and VII.

@article{Mineo1985ExcessPD,
  title={Excess purine degradation in exercising muscles of patients with glycogen storage disease types V and VII.},
  author={Ikuo Mineo and Norio Kono and Takao Shimizu and Naoko Hara and Yuya Yamada and Shoichiro Sumi and Kenji Nonaka and Seiichiro Tarui},
  journal={The Journal of clinical investigation},
  year={1985},
  volume={76 2},
  pages={556-60}
}
To investigate purine catabolism in exercising muscles of patients with muscle glycogen storage disease, we performed ischemic forearm exercise tests and quantitated metabolites appearing in cubital venous blood. Two patients with glycogen storage disease type V and three with glycogen storage disease type VII participated in this study. Basal lactate concentrations lowered in every patient with glycogen storage disease type V or type VII. Two patients with glycogen storage disease type VII… CONTINUE READING