Excess production of phage lambda delayed early proteins under conditions supporting high Escherichia coli growth rates.

@article{Gabig1998ExcessPO,
  title={Excess production of phage lambda delayed early proteins under conditions supporting high Escherichia coli growth rates.},
  author={Magdalena Gabig and Michał Obuchowski and Alicja Węgrzyn and Agnieszka Szalewska-Pałasz and Mark S Thomas and Grzegorz Węgrzyn},
  journal={Microbiology},
  year={1998},
  volume={144 ( Pt 8)},
  pages={2217-24}
}
Bacteriophage lambda is unable to lysogenize Escherichia coli hosts harbouring the rpoA341 mutation due to a drastic reduction in transcription from CII-activated lysogenic promoters (pE, pI and paQ). In addition, the level of early transcripts involved in the lytic pathway of lambda development is also decreased in this genetic background due to impaired N-dependent antitermination. Here, it is demonstrated that despite the reduced level of early lytic pL- and pR-derived transcripts, lytic… CONTINUE READING