Excess haemoglobin digestion by malaria parasites: a strategy to prevent premature host cell lysis.

@article{Lew2004ExcessHD,
  title={Excess haemoglobin digestion by malaria parasites: a strategy to prevent premature host cell lysis.},
  author={Virgilio L. Lew and Lynn E. Macdonald and Hagai Ginsburg and Miriam Krugliak and Teresa Tiffert},
  journal={Blood cells, molecules & diseases},
  year={2004},
  volume={32 3},
  pages={353-9}
}
To understand the osmotic stability of a Plasmodium falciparum-infected red blood cell, whose membrane permeability becomes highly increased during parasite growth, we developed an integrated mathematical model of the homeostasis of an infected red cell. The model encoded the known time courses of red cell membrane permeabilisation and of haemoglobin… CONTINUE READING