Excess estrogen sulfoconjugation as the possible cause for a poor sign of parturition in pregnant cows carrying somatic cell clone fetuses.

@article{Hirayama2008ExcessES,
  title={Excess estrogen sulfoconjugation as the possible cause for a poor sign of parturition in pregnant cows carrying somatic cell clone fetuses.},
  author={Hiroki Hirayama and Ken Roger Sawai and Satoru Moriyasu and Muneyuki Hirayama and Yuji Goto and Etsushi Kaneko and Akio Miyamoto and Koichi Ushizawa and Toru Takahashi and Akira Minamihashi},
  journal={Reproduction},
  year={2008},
  volume={136 5},
  pages={639-47}
}
We conducted this study to elucidate a factor causing a poor sign of parturition and prolonged gestation, which is frequently observed in cows carrying somatic clone fetuses. Pre-partum rises in concentrations of plasma estrone and estradiol-17beta in the recipient cows pregnant with clones were subtle. By contrast, the plasma concentration of estrone sulfate in clone pregnancies increased gradually from pre-initiation of parturition induction whereas control cows that received in vivo-derived… CONTINUE READING
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