Excess Mortality Associated With Colistin-Tigecycline Compared With Colistin-Carbapenem Combination Therapy for Extensively Drug-Resistant Acinetobacter baumannii Bacteremia: A Multicenter Prospective Observational Study.

@article{Cheng2015ExcessMA,
  title={Excess Mortality Associated With Colistin-Tigecycline Compared With Colistin-Carbapenem Combination Therapy for Extensively Drug-Resistant Acinetobacter baumannii Bacteremia: A Multicenter Prospective Observational Study.},
  author={Aristine Cheng and Yu-Chung Chuang and H Sun and W M Sheng and Chia-Jui Yang and C Liao and Po Ren Hsueh and Jia-Ling Yang and Ni-Jiin Shen and Jann-Tay Wang and Chien-Ching Hung and Yee-Chun Chen and S -S Chang},
  journal={Critical care medicine},
  year={2015},
  volume={43 6},
  pages={1194-204}
}
OBJECTIVES Since few therapeutic options exist for extensively drug resistant Acinetobacter baumannii, an emerging threat in ICUs worldwide, and comparative prospective studies of colistin-based combination therapies are lacking, our objective was to compare the outcomes of patients with extensively drug-resistant A. baumannii bacteremia, treated with colistin-carbapenem and colistin-tigecycline combinations. DESIGN Prospective, observational, multicenter study. SETTING, PATIENTS, AND… CONTINUE READING
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