Exceptional body composition changes attributed to collagen peptide supplementation and resistance training in older sarcopenic men

  title={Exceptional body composition changes attributed to collagen peptide supplementation and resistance training in older sarcopenic men},
  author={Stuart M Phillips and Kevin D Tipton and Luc J. C. van Loon and Lex B. Verdijk and Douglas Paddon-Jones and Graeme L. Close},
  journal={British Journal of Nutrition},
  pages={569 - 570}
Abstract The results reported by Zdzieblik et al.(1), on gains in fat-free mass (FFM: mean 4·2 (SD 3·3) kg) and loss of body fat (mean −5·5 (SD 3·2) kg) in older sarcopenic men receiving 15 g/d of collagen peptides while resistance training for 12 weeks, are extraordinary. The algebraic difference between the collagen peptide-supplemented and placebo groups in terms of FFM reported by Zdzieblik et al.(1) was approximately 1·3 kg, which is 2·7 and 5·6 times greater than the standardised mean… 
Whey Protein Supplementation Compared to Collagen Increases Blood Nesfatin Concentrations and Decreases Android Fat in Overweight Women: A Randomized Double-Blind Study
Whey protein supplementation in overweight women increased nesfatin concentrations and could promote increase of resting metabolic rate as part of body composition improvement programs compared to collagen supplementation for 8 weeks, suggesting that collagen may not be an effective supplement for overweight women who are attempting to alter body composition.
A randomized controlled trial of the impact of protein supplementation on leg lean mass and integrated muscle protein synthesis during inactivity and energy restriction in older persons.
Protein supplementation did not confer a benefit in protecting LLM, but only supplemental WP augmented LLM and muscle protein synthesis during recovery from inactivity and a hypoenergetic state.
Whey protein but not collagen peptides stimulate acute and longer-term muscle protein synthesis with and without resistance exercise in healthy older women: a randomized controlled trial.
BACKGROUND Aging appears to attenuate the response of skeletal muscle protein synthesis (MPS) to anabolic stimuli such as protein ingestion (and the ensuing hyperaminoacidemia) and resistance
A Collagen Hydrolysate Containing Tripeptides Ameliorates Sarcopenia in Middle-Aged Mice
CP and CTP ameliorate age-associated sarcopenia through different mechanisms that increase the weight of the quadriceps tibialis anterior and gastrocnemius muscles and reduced body fat.
Effects of Collagen Peptides on Recovery Following Eccentric Exercise in Resistance-Trained Males-A Pilot Study.
Acute consumption of CP may provide a performance benefit the day following a bout of damaging exercise in resistance-trained males and showed a significant time effect over the 5-day postexercise period.
Animal, Plant, Collagen and Blended Dietary Proteins: Effects on Musculoskeletal Outcomes
This review evaluates the efficacy of animal-, plant- and collagen-derived proteins in isolation, and as protein blends, for augmenting muscle and bone metabolism and health in the context of ageing, exercise and energy restriction.
Protecting Skeletal Muscle with Protein and Amino Acid during Periods of Disuse
Emerging evidence suggests that leucine supplemented meals may partially and temporarily protect skeletal muscle during disuse by preserving anabolism and mitigating reductions in mass, function and metabolic homeostasis.
High-Protein Diet Containing Dairy Products is Associated with Low Body Mass Index and Glucose Concentrations: A Cross-Sectional Study
A high-protein diet containing dairy food, in particular two servings of cheese, was associated with low BMI and random glucose concentration and reduced the risk of having high blood glucose levels by approximately 80%.
Variation in Protein Origin and Utilization: Research and Clinical Application
  • S. McClave, R. Hurt, J. Wernerman
  • Medicine, Biology
    Nutrition in clinical practice : official publication of the American Society for Parenteral and Enteral Nutrition
  • 2017
Choosing parenteral and/or enteral feeding options that contain high-quality proteins, rich in the branched-chain amino acid leucine, may help establish a dietary framework with the potential to support clinical practice and improve health outcomes in critically ill patients.
Protein Kinetics and Metabolic Effects Related to Disease States and Sepsis
A set of recommendations based on assessment of the current literature to guide healthcare professionals in clinical practice at this time, as well as a list of potential topics to guide investigators for purposes of research in the future are provided.


Collagen peptide supplementation in combination with resistance training improves body composition and increases muscle strength in elderly sarcopenic men: a randomised controlled trial
The data demonstrate that compared with placebo, collagen peptide supplementation in combination with resistance training further improved body composition by increasing FFM, muscle strength and the loss in FM.
Skeletal muscle adaptations to testosterone and resistance training in men with COPD.
The data suggest that the combined interventions produced an enhanced local anabolic milieu driven in large part by the muscle IGF system, despite potentially negative biochemical influences present in COPD patients.
Effects of Protein Supplementation in Older Adults Undergoing Resistance Training: A Systematic Review and Meta-Analysis
Combining protein supplementation with resistance training is effective for eliciting gains in fat-free mass among older adults, but does not seem to increase muscle mass or strength.
Bolus arginine supplementation affects neither muscle blood flow nor muscle protein synthesis in young men at rest or after resistance exercise.
It is concluded that an oral bolus (10 g) of arginine does not increase NO synthesis or muscle blood flow or enhance mixed or myofibrillar MPS either at rest or after resistance exercise beyond that achieved by feeding alone.
Protein ingestion to stimulate myofibrillar protein synthesis requires greater relative protein intakes in healthy older versus younger men.
The data suggest that healthy older men are less sensitive to low protein intakes and require a greater relative protein intake, in a single meal, than young men to maximally stimulate postprandial rates of MPS.
Exercise attenuates the weight-loss-induced reduction in muscle mass in frail obese older adults.
Regular exercise that incorporates PRT should be used to attenuate muscle mass loss in frail obese older adults on weight-loss therapy.
Protein supplementation augments the adaptive response of skeletal muscle to resistance-type exercise training: a meta-analysis.
Protein supplementation increases muscle mass and strength gains during prolonged resistance-type exercise training in both younger and older subjects.
Citrulline does not enhance blood flow, microvascular circulation, or myofibrillar protein synthesis in elderly men at rest or following exercise.
Citrulline coingestion with a low quantity of protein was ineffective in augmenting the anabolic properties of protein compared with nonessential amino acids.