Examining the role of macrolides and host immunity in combatting filarial parasites

Abstract

Macrocyclic lactones (MLs), specifically the avermectins and milbemycins, are known for their effectiveness against a broad spectrum of disease-causing nematodes and arthropods in humans and animals. In most nematodes, drugs in this class induce paralysis, resulting in starvation, impaired ability to remain associated with their anatomical environment, and… (More)
DOI: 10.1186/s13071-017-2116-6

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