• Corpus ID: 16773687

Examining the efficacy of silver and cadexomer iodine dressings in treating wounds compromised by bacterial burden : A review of the literature

  title={Examining the efficacy of silver and cadexomer iodine dressings in treating wounds compromised by bacterial burden : A review of the literature},
  author={Antonio M{\'e}ndez-Vilas},
Topical antimicrobial agents provide an opportunity to prevent the spread of bacterial burden beyond critical colonisation and local infection, aid in the swift and effective management of systemic infection, reduce excessive and prolonged use of antibiotic therapy for people living with chronic wounds [1, 2], and reduce the risk of developing bacterial resistance associated with the use of antibiotics. The role of topical antimicrobials is well established within the principles of wound bed… 


The role of Acticoat with nanocrystalline silver in the management of burns.
A review of the microbiology, antibiotic usage and resistance in chronic skin wounds.
The evidence and role of antibiotics in the treatment of chronic wounds are outlined and current practice of antibiotic usage for chronic wounds in the primary care setting described, and the implications of antibiotics usage with regard to antibiotic resistance are considered.
A randomized‐controlled trial comparing cadexomer iodine and nanocrystalline silver on the healing of leg ulcers
  • Charne Miller, N. Newall, N. Santamaria
  • Medicine
    Wound repair and regeneration : official publication of the Wound Healing Society [and] the European Tissue Repair Society
  • 2010
The performance of each of the two antimicrobials was comparable in terms of overall healing rate and the number of wounds healed, but use of silver compounds was associated with a quicker healing rate during the first 2 weeks of treatment and in wounds that were larger, older, and had more exudate.
Antiseptics on Wounds: An Area of Controversy
The authors found that despite cytotoxicty data, most antiseptics have not been shown to clearly impede healing, especially newer formulations like cadexomer� iodine (which speeds healing) and novel silver delivery systems.
Topical antimicrobial therapy for treating chronic wounds.
  • Benjamin A Lipsky, C. Hoey
  • Medicine, Biology
    Clinical infectious diseases : an official publication of the Infectious Diseases Society of America
  • 2009
Clinical relevant information is provided on currently available topical antimicrobial agents used to treat infected wounds and how to treat poorly healing wounds with "secondary" signs suggesting infection.
Use of Acticoat dressings in burns: what is the evidence?
Topical silver‐impregnated dressings and the importance of the dressing technology
The evidence for the ancillary function(s) of the dressing will become differentiating factors that influence choice are presented, thereby enabling practitioners to evaluate comparative dressing attributes and make an informed choice of which silver dressing best suits the needs of the wound under differing circumstances.
Screening evaluation of an ionized nanocrystalline silver dressing in chronic wound care.
The proposed mechanism of action for this ionized nanocrystalline based dressing is through bacterial and moisture balance within the superficial wound space compartment, and showed a marked clinical improvement for the majority of wounds treated with the dressing.
Evaluating and managing open skin wounds: colonization versus infection.
  • A. Wysocki
  • Medicine, Biology
    AACN clinical issues
  • 2002
A targeted review of normal skin flora, wound healing, prevention of skin infection, colonization versus infection, biofilms, genomics and infectious disease, and management of open skin wounds is provided.
Evaluation of a silver-releasing hydroalginate dressing in chronic wounds with signs of local infection.
This study suggests that the use of silver-releasing dressings in the management of wounds at high risk of infection may have a clinically favourable influence on wound prognosis; the dressings also appeared to be well tolerated.