Examining the efficacy of adjunctive aripiprazole in major depressive disorder: a pooled analysis of 2 studies.

@article{Thase2008ExaminingTE,
  title={Examining the efficacy of adjunctive aripiprazole in major depressive disorder: a pooled analysis of 2 studies.},
  author={Michael E. Thase and Madhukar H. Trivedi and James C. Nelson and Maurizio Fava and Ren{\'e} Swanink and Q Canh Tran and Andrei S Pikalov and Huyuan Yang and Berit X Carlson and Ronald N. Marcus and Robert M. Berman},
  journal={Primary care companion to the Journal of clinical psychiatry},
  year={2008},
  volume={10 6},
  pages={440-7}
}
BACKGROUND Patients with major depressive disorder (MDD) who fail to achieve complete remission with antidepressant therapy may benefit from augmentation therapy with an atypical antipsychotic. METHOD A pooled analysis was performed on 2 identical 14-week studies (8-week prospective antidepressant therapy treatment phase followed by 6-week randomized double-blind phase) evaluating the efficacy of adjunctive aripiprazole (2-20 mg/day) in DSM-IV-TR-defined MDD patients with an inadequate… CONTINUE READING
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