Examining nitroxyl in biological systems.

  title={Examining nitroxyl in biological systems.},
  author={Jon M Fukuto and Matthew I. Jackson and Nina Kaludercic and Nazareno Paolocci},
  journal={Methods in enzymology},
Nitroxyl (HNO) has received significant recent attention due to its remarkable and novel biological activity and pharmacological potential. Unlike most other commonly studied nitrogen oxides, examination of HNO biology is not straightforward because of its unique chemical properties. Thus, the study of HNO in biological system requires researchers to be aware of this chemistry in order to properly design and interpret experiments. This chapter focuses on the experimental issues associated with… CONTINUE READING

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