Examining expression of folate receptor in squamous cell carcinoma of the head and neck as a target for a novel nanotherapeutic drug.

@article{Saba2009ExaminingEO,
  title={Examining expression of folate receptor in squamous cell carcinoma of the head and neck as a target for a novel nanotherapeutic drug.},
  author={Nabil F. Saba and Xu Wang and Susan S. Mueller and Mourad Tighiouart and Kwangjae Cho and Shuming Nie and Zhuo Georgia Chen and Dong M Shin},
  journal={Head & neck},
  year={2009},
  volume={31 4},
  pages={475-81}
}
BACKGROUND Nanotechnology-based drug delivery approaches may help increase therapeutic efficacy and decrease side effects of chemotherapeutics. We investigated expression levels of folate receptor in squamous cell carcinoma of the head and neck (SCCHN) to evaluate folate receptor as a target for nanotherapy. METHODS Folate receptor expression levels in archival SCCHN tissues were analyzed by immunohistochemistry and correlated with clinical parameters. RESULTS Folate receptor was detected… CONTINUE READING
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