Examining a pathway for hormone mediated maternal effects--yolk testosterone affects androgen receptor expression and endogenous testosterone production in young chicks (Gallus gallus domesticus).

@article{Pfannkuche2011ExaminingAP,
  title={Examining a pathway for hormone mediated maternal effects--yolk testosterone affects androgen receptor expression and endogenous testosterone production in young chicks (Gallus gallus domesticus).},
  author={Kristina A Pfannkuche and Manfred Gahr and Ilse Weites and Bernd Riedstra and Carl F W Wolf and Ton G. G. Groothuis},
  journal={General and comparative endocrinology},
  year={2011},
  volume={172 3},
  pages={487-93}
}
In vertebrates maternal androgens can substantially influence developing offspring, inducing both short and long term changes in physiology and behavior, including androgen sensitive traits. However, how the effects of maternal hormones are mediated remains unknown. Two possible pathways are that maternal androgens affect parts of the hypothalamus-pituitary-gonadal axis (HPG axis) or the sensitivity to androgens by affecting androgen receptor (AR) densities within the brain. To investigate both… CONTINUE READING
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