Examining F-actin interaction with intact talin and talin head and tail fragment using static and dynamic light scattering.

@article{Goldmann1997ExaminingFI,
  title={Examining F-actin interaction with intact talin and talin head and tail fragment using static and dynamic light scattering.},
  author={Wolfgang Heinrich Goldmann and Zeno von Guttenberg and Stefan Kaufmann and David M. Hess and Robert M. Ezzell and Gerhard Isenberg},
  journal={European journal of biochemistry},
  year={1997},
  volume={250 2},
  pages={447-50}
}
We examined the binding kinetics of intact talin and talin head and tail fragment with F-actin at pH 7.0 and at low ionic strength. We observed by a transient kinetic method a fast followed by a slower binding process for intact talin and talin tail fragment with filamentous actin. The latter can be attributed to F-actin cross-linking and/or bundling, which… CONTINUE READING