Examination of the inhibitory effects of interferon-gamma on interleukin-4-induced stimulation of resting B cells from NZB/NZW F1 mice.

@article{Minoda1989ExaminationOT,
  title={Examination of the inhibitory effects of interferon-gamma on interleukin-4-induced stimulation of resting B cells from NZB/NZW F1 mice.},
  author={Masahiko Minoda and Koichi Hamada and Masahiko Higashikawa and H Sugishima and Masunori Funauchi and Akiko Horiuchi},
  journal={Clinical and experimental immunology},
  year={1989},
  volume={78 1},
  pages={115-9}
}
Percoll fractionation of NZB/NZW F1 mouse B cells revealed an increased ratio of low-density fraction ('activated' B cell fraction) and a decreased ratio of high-density fraction ('resting' B cell fraction), in comparison to normal mouse B cells. Resting B cells of B/W F1 mice were hyperresponsive to interleukin-4 (IL-4), with increased proliferation and… CONTINUE READING