Examination of the Combined Effects of Chondroitinase ABC, Growth Factors and Locomotor Training following Compressive Spinal Cord Injury on Neuroanatomical Plasticity and Kinematics

@inproceedings{Alluin2014ExaminationOT,
  title={Examination of the Combined Effects of Chondroitinase ABC, Growth Factors and Locomotor Training following Compressive Spinal Cord Injury on Neuroanatomical Plasticity and Kinematics},
  author={Olivier Alluin and H. Delivet-Mongrain and Marie-Krystel Gauthier and Michael G. Fehlings and Serge Rossignol and Soheila Karimi-Abdolrezaee},
  booktitle={PloS one},
  year={2014}
}
While several cellular and pharmacological treatments have been evaluated following spinal cord injury (SCI) in animal models, it is increasingly recognized that approaches to address the glial scar, including the use of chondroitinase ABC (ChABC), can facilitate neuroanatomical plasticity. Moreover, increasing evidence suggests that combinatorial strategies are key to unlocking the plasticity that is enabled by ChABC. Given this, we evaluated the anatomical and functional consequences of ChABC… CONTINUE READING
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Spinal plasticity underlying the recovery of locomotion after injury

  • SS B.J.Rossignol, L. M Jordan
  • 2014

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