Examination of lung toxicity, oxidant/antioxidant status and effect of erdosteine in rats kept in coal mine ambience.

@article{Armutu2007ExaminationOL,
  title={Examination of lung toxicity, oxidant/antioxidant status and effect of erdosteine in rats kept in coal mine ambience.},
  author={Ferah Armutçu and Banu Dogan Gun and Remzi Altin and Ahmet Gurel},
  journal={Environmental toxicology and pharmacology},
  year={2007},
  volume={24 2},
  pages={106-13}
}
Occupational exposure to coal dust causes pneumoconiosis and other diseases. Reactive oxygen species (ROS) have been implicated in the pathogenesis of coal dust-induced lung toxicity. In this experimental study, we investigated the oxidant/antioxidant status, nitric oxide (NO) and hydroxyproline (HP) levels in lungs and blood of rats exposed to coal dust in mine ambience. In addition, we also investigated the attenuating effects of erdosteine. At the end of the experiment processes, tissue… CONTINUE READING