Examination of a palatogenic gene program in zebrafish.

@article{Swartz2011ExaminationOA,
  title={Examination of a palatogenic gene program in zebrafish.},
  author={Mary E Swartz and Kelly Sheehan-Rooney and Michael James Dixon and Johann K. Eberhart},
  journal={Developmental dynamics : an official publication of the American Association of Anatomists},
  year={2011},
  volume={240 9},
  pages={2204-20}
}
Human palatal clefting is debilitating and difficult to rectify surgically. Animal models enhance our understanding of palatogenesis and are essential in strategies designed to ameliorate palatal malformations in humans. Recent studies have shown that the zebrafish palate, or anterior neurocranium, is under similar genetic control to the amniote palatal skeleton. We extensively analyzed palatogenesis in zebrafish to determine the similarity of gene expression and function across vertebrates. By… CONTINUE READING
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