Examination of Alternaria alternata mutagenicity and effects of nitrosylation using the Ames Salmonella test.

@article{Schrader2001ExaminationOA,
  title={Examination of Alternaria alternata mutagenicity and effects of nitrosylation using the Ames Salmonella test.},
  author={Tim J. Schrader and W Brett Cherry and Kate Soper and Ingrid Langlois and Hari M Vijay},
  journal={Teratogenesis, carcinogenesis, and mutagenesis},
  year={2001},
  volume={21 4},
  pages={261-74}
}
Molds of the genus Alternaria are common food pathogens responsible for the spoilage of fruits, vegetables, grains, and nuts. Although consumption of Alternaria alternata-contaminated foodstuffs has been implicated in an elevated incidence of esophageal carcinogenesis, the mutagenic potencies of several A. alternata toxins seem unable to account for the levels of activity found using crude mycelial extracts. In this study, the mutagenic effects of nitrosylation were examined with the major… CONTINUE READING

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