Exaggeration of postprandial hyperglycemia in patients with type 2 diabetes by administration of caffeine in coffee.

@article{Lane2007ExaggerationOP,
  title={Exaggeration of postprandial hyperglycemia in patients with type 2 diabetes by administration of caffeine in coffee.},
  author={James D. Lane and Allen L. Hwang and Mark Feinglos and Richard S. Surwit},
  journal={Endocrine practice : official journal of the American College of Endocrinology and the American Association of Clinical Endocrinologists},
  year={2007},
  volume={13 3},
  pages={
          239-43
        }
}
  • J. D. Lane, Allen L. Hwang, +1 author R. Surwit
  • Published 1 May 2007
  • Medicine
  • Endocrine practice : official journal of the American College of Endocrinology and the American Association of Clinical Endocrinologists
OBJECTIVE To test whether caffeine administered in coffee increases postprandial hyperglycemia in patients with type 2 diabetes who are habitual coffee drinkers. METHODS The study used a within-subject, double-blind, placebo-controlled experimental design. Twenty adult coffee drinkers (11 women and 9 men) with type 2 diabetes treated with diet, exercise, orally administered antidiabetic agents, or some combination of these factors completed two mixed-meal tolerance tests (MMTT) after an… 
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TLDR
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Black espresso coffee in people with type 2 diabetes mellitus results in a marginally greater excursion of glucose during a following OGTT compared with water or decaffeinated coffee, and this effect does not appear to be mediated by changes in insulin sensitivity.
Consumption of caffeinated coffee and a high carbohydrate meal affects postprandial metabolism of a subsequent oral glucose tolerance test in young, healthy males
TLDR
Co-ingestion of CC with one meal resulted in insulin insensitivity during the postprandial phase of a second meal in the absence of further CC ingestion, suggesting that CC may play a role in daily glycaemic management.
Caffeine, Glucose Metabolism, and Type 2 Diabetes
TLDR
Although it is premature to recommend caffeine abstinence for patients with T2DM, the results of these well-controlled experimental studies contradict epidemiological studies that find that heavy coffee drinking is associated with a lower risk of T2 DM.
Performance effects and metabolic consequences of caffeine and caffeinated energy drink consumption on glucose disposal.
TLDR
Both caffeine-induced performance enhancement and insulin resistance converge with the primary actions of caffeine on skeletal muscle, which may have implications for the development of a number of chronic diseases.
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