Exaggerated eye growth in IRBP-deficient mice in early development.


PURPOSE Because interphotoreceptor retinoid-binding protein (IRBP) is expressed before being needed in its presumptive role in the visual cycle, we tested whether it controls eye growth during development. METHODS The eyes of congenic IRBP knockout (KO) and C57BL/6J wild-type (WT) mice ranging in age from postnatal day (P)2 to P440 were compared by… (More)
DOI: 10.1167/iovs.10-7129


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