Exaggerated avoidance of novel stimulation in rats partially recovered from central norepinephrine damage.

Rats in which central norepinephrine lesions are made with 6-OHDA and a recovery period allowed show a behavioral syndrome distinct from controls, from rats with more extensive norepinephrine damage (lesioned with 6-OHDA, allowed to recover, and relesioned), and from rats with general depletion of serotonin (chronic PCPA). These rats administered central 6… CONTINUE READING