Exaggerated TSH responses to TRH in depressed patients with "normal" baseline TSH.

@article{Kraus1997ExaggeratedTR,
  title={Exaggerated TSH responses to TRH in depressed patients with "normal" baseline TSH.},
  author={Rolf Kraus and E Phoenix and Melisa Edmonds and Ian R. Nicholson and Praful Chandarana and Sonya Tokmakejian},
  journal={The Journal of clinical psychiatry},
  year={1997},
  volume={58 6},
  pages={266-70}
}
BACKGROUND Subclinical hypothyroidism (elevated thyroid-stimulating hormone [TSH] with normal thyroid hormone levels) can present with depression. This may be confirmed by an exaggerated TSH response to thyrotropin-releasing hormone (TRH) on the TRH stimulation test (TRH-ST). The objective of this study was to determine the prevalence of exaggerated TRH-ST results in a sample of depressed patients with "high-normal" screening TSH levels. METHOD Depressed patients with TSH levels of 3.00-5.50… CONTINUE READING