Exact solution of the Muñoz-Eaton model for protein folding.

  title={Exact solution of the Mu{\~n}oz-Eaton model for protein folding.},
  author={Pierpaolo Bruscolini and Alessandro Pelizzola},
  journal={Physical review letters},
  volume={88 25 Pt 1},
A transfer-matrix formalism is introduced to evaluate exactly the partition function of the Muñoz-Eaton model, relating the folding kinetics of proteins of known structure to their thermodynamics and topology. This technique can be used for a generic protein, for any choice of the energy and entropy parameters, and in principle allows the model to be used as a first tool to characterize the dynamics of a protein of known native state and equilibrium population. Applications to a beta-hairpin… CONTINUE READING