Exact solution of a two-type branching process: Clone size distribution in cell division kinetics

@inproceedings{Antal2009ExactSO,
  title={Exact solution of a two-type branching process: Clone size distribution in cell division kinetics},
  author={Tibor Antal and Pavel L Krapivsky},
  year={2009}
}
We study a two-type branching process which provides excellent description of experimental data on cell dynamics in skin tissue (Clayton et al., 2007). The model involves only a single type of progenitor cell, and does not require support from a self-renewed population of stem cells. The progenitor cells divide and may differentiate into postmitotic cells. We derive an exact solution of this model in terms of generating functions for the total number of cells, and for the number of cells of… CONTINUE READING

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