Exact multipoint quantitative-trait linkage analysis in pedigrees by variance components.

  • S C Pratt, M J Daly, L Kruglyak
  • Published 2000 in American journal of human genetics

Abstract

Methods based on variance components are powerful tools for linkage analysis of quantitative traits, because they allow simultaneous consideration of all pedigree members. The central idea is to identify loci making a significant contribution to the population variance of a trait, by use of allele-sharing probabilities derived from genotyped marker loci… (More)

Cite this paper

@article{Pratt2000ExactMQ, title={Exact multipoint quantitative-trait linkage analysis in pedigrees by variance components.}, author={S C Pratt and M J Daly and L Kruglyak}, journal={American journal of human genetics}, year={2000}, volume={66 3}, pages={1153-7} }