Exacerbation or Unmasking of Focal Neurologic Deficits by Sedatives

  title={Exacerbation or Unmasking of Focal Neurologic Deficits by Sedatives},
  author={Gary Thal and Michele D. Szabo and Maria V. Lopez-Bresnahan and Gregory J. Crosby},
Background Transient focal neurologic deficits have been observed in patients emerging from brain tumor or carotid surgery, and a pharmacologic effect of anesthetic agents has been proposed as the cause of such neurologic dysfunction. Therefore, the effect of sedation with midazolam or fentanyl on motor neurologic function was studied prospectively and preoperatively in patients with carotid disease or mass lesions of the brain. Methods Fifty-four unpremedicated adult patients with carotid… 

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