Exacerbating role of gammadelta T cells in chronic colitis of T-cell receptor alpha mutant mice.

Abstract

BACKGROUND & AIMS T-cell receptor (TCR) gammadelta T cells are an important component of the mucosal immune system and regulate intestinal epithelial homeostasis. Interestingly, there is a significant increase in gammadelta T cells in the inflamed mucosa of patients with ulcerative colitis (UC). However, the role of gammadelta T cells in chronic colitis has… (More)
DOI: 10.1053/j.gastro.2007.11.056

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