Ex vivo biocompatibility evaluation of a new modified cellulose membrane.

  title={Ex vivo biocompatibility evaluation of a new modified cellulose membrane.},
  author={T. Bosch and B. Schmidt and P. C. Spencer and W. Samtleben and M. Pelger and U. Baurmeister and H. Gurland},
  journal={Artificial organs},
  volume={11 2},
  • T. Bosch, B. Schmidt, +4 authors H. Gurland
  • Published 1987
  • Medicine
  • Artificial organs
  • To evaluate membrane biocompatibility, an open loop ex vivo model was designed simulating the hemodialysis procedure. Blood was withdrawn continuously from healthy nonuremic donors, heparinized, and pumped through a module containing the membrane to be studied. C3a generation in the module was determined at various time points comparing the cuprammonium cellulose (CC) membrane and four types of modified cellulose (MC) membrane, each with a different degree of hydroxyl (OH-) group substitution… CONTINUE READING
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