Ewing sarcoma-peripheral neuroectodermal tumor of the kidney with a FUS-ERG fusion transcript.

@article{Berg2009EwingSN,
  title={Ewing sarcoma-peripheral neuroectodermal tumor of the kidney with a FUS-ERG fusion transcript.},
  author={Thomas Berg and Ann-Hilde Kalsaas and Jochen Buechner and Lill-Tove Rasmussen Busund},
  journal={Cancer genetics and cytogenetics},
  year={2009},
  volume={194 1},
  pages={
          53-7
        }
}
The Ewing family of tumors (EFTs) represents a neoplastic entity characterized by specific chromosomal rearrangements. The most commonly detected translocation involves fusion of EWSR1 to one of the genes encoding ETS family of transcription factors, usually FLI1 or ERG. In rare cases, FUS or FEV has been shown to substitute for EWSR1. The detection of specific translocations by fluorescence in situ hybridization (FISH), reverse transcription-polymerase chain reaction (RT-PCR), or both has… CONTINUE READING

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