Evolving views of the major histocompatibility complex.

  title={Evolving views of the major histocompatibility complex.},
  author={Jeffrey R. Gruen and Sherman Morton Weissman},
  volume={90 11},
T of parts of the MHC has grown substantially within the last year. HE MAJOR HISTOCOMPATIBILITY complex (MHC) is an extended cluster of genes that are remarkable for the number and importance of the immunological functions The MHC is of major biomedical interest because of its contribution to transplant rejection and to variation between they encode. Historically, interest in the MHC emanated from tissue transplantation experiments, hence the reference to histoindividuals in susceptibility to a… CONTINUE READING