Evolving pharmacological approaches in gastroesophageal reflux disease

@article{Altan2012EvolvingPA,
  title={Evolving pharmacological approaches in gastroesophageal reflux disease},
  author={E. Altan and K. Blondeau and A. Pauwels and R. Farr{\'e} and J. Tack},
  journal={Expert Opinion on Emerging Drugs},
  year={2012},
  volume={17},
  pages={347 - 359}
}
  • E. Altan, K. Blondeau, +2 authors J. Tack
  • Published 2012
  • Medicine
  • Expert Opinion on Emerging Drugs
  • Introduction: Proton pump inhibitors (PPIs) have considerably improved quality of life in patients with gastroesophageal reflux disease (GERD). However, many patients remain symptomatic despite standard PPI therapy. Areas covered: This review focuses on evolving therapeutic strategies related to the pathophysiological processes of GERD and insufficient response to PPIs. Several clinical trials evaluated new PPI formulations and newer types of acid-suppressive drugs. These studies have evaluated… CONTINUE READING
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