Evolving Landscape of Clinical Trials in Heart Failure: Patient Populations, Endpoint Selection, and Regions of Enrollment.

@article{Tahhan2018EvolvingLO,
  title={Evolving Landscape of Clinical Trials in Heart Failure: Patient Populations, Endpoint Selection, and Regions of Enrollment.},
  author={Ayman Samman Tahhan and Muthiah Vaduganathan and Stephen J. Greene and Maureen Okafor and Sonali Kumar and Javed Butler},
  journal={Current heart failure reports},
  year={2018},
  volume={15 1},
  pages={
          10-16
        }
}
PURPOSE OF REVIEW Clinical trial design and execution are evolving as increasingly important considerations with respect to the success of heart failure trials. The current review highlights temporal trends in characteristics of heart failure clinical trials. RECENT FINDINGS Recent trials in heart failure have required longer recruitment phases, displayed inefficient enrollment rates, increased use of composite and nonfatal endpoints, undergone rapid globalization, and gradually increased… CONTINUE READING
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